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That Wasn't a Complement-Too Much C3 in Demyelinating Disease.

Xin, Wendy; Chan, Jonah R.
Immunity; 52(1): 11-13, 2020 01 14.
Artigo em Inglês | MEDLINE | ID: mdl-31951547
Multiple sclerosis is a chronic inflammatory disease characterized by demyelination in the central nervous system. In this issue of Immunity, Werneberg et al. report a striking loss of synapses driven by excessive microglial pruning early in demyelinating disease, which can be rescued by inhibiting the complement component C3.
Selo DaSilva