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Advanced Cutaneous Squamous Cell Carcinoma Is Associated with Suboptimal Initial Management in a Cohort of 109 Patients.

Deilhes, Florian; Boulinguez, Serge; Pagès, Cécile; Paul, Carle; Meyer, Nicolas.
Dermatology; : 1-6, 2019 Aug 06.
Artigo em Inglês | MEDLINE | ID: mdl-31387094


Little is known about the epidemiological characteristics of patients with advanced cutaneous squamous cell carcinoma (A-cSCC).


A retrospective study was conducted on a routine care cohort of 109 patients to identify the epidemiological factors associated with A-cSCC.


The median age was 83 years (IQR: 73.9-89.8), and the median ECOG was 1 (IQR: 1-2). Sixty percent of the patients had a history of cardiac disease and 22% had cognitive disorders. Seventy-four percent of patients were from rural/semi-rural areas (towns of <15,000 residents) and 17% were living in nursing homes. The cSCC lesions were on the head and neck in 72% of cases. Thirty-seven percent of patients were not diagnosed until the disease was in an advanced stage, indicating a lack of cSCC identification. In the remaining 69 patients, 7% did not received treatment within 3 months of the cSCC being identified, 62% had an incomplete histological report, and 37% had incomplete treatment.


A-cSCC is associated with incomplete initial treatment in an elderly and rural population with good general condition. We hypothesize that a lack of access to good dermatological expertise may have led to underestimation of the aggressiveness of cSCC and/or therapeutic mismanagement.
Selo DaSilva