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Association between Type D personality and outcomes in patients with non-ischemic heart failure.

Bundgaard, Johan S; Østergaard, Lauge; Gislason, Gunnar; Thune, Jens J; Nielsen, Jens C; Haarbo, Jens; Videbæk, Lars; Olesen, Line L; Thøgersen, Anna M; Torp-Pedersen, Christian; Pedersen, Susanne S; Køber, Lars; Mogensen, Ulrik M.
Qual Life Res; 28(11): 2901-2908, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31292822

PURPOSE:

The "distressed" (Type D) personality trait has been reported to be over-represented in patients with heart failure (HF) compared to the background population and may provide prognostic information for mortality. We examined the association between Type D personality and outcomes in the DANISH trial (The Danish Study to Assess the Efficacy of Implantable Cardioverter Defibrillators in Patients with Non-ischemic Systolic Heart Failure on Mortality).

METHODS:

The DANISH trial included a total of 1116 patients with non-ischemic HF on guideline-recommended therapy. Type D personality was assessed with the Type D Scale (DS14) at baseline and investigated through follow-up accordingly. Multivariable Cox proportional hazard models were used to compare hazard ratios (HR) of cardiovascular and all-cause mortality.

RESULTS:

Type D personality assessment was completed by 873 (78%) patients at baseline and Type D personality was found in 120 (14%) patients. The median follow-up was 67 months (interquartile range [IQR] 48-83). Among patients with versus without Type D personality, 22% versus 19% died from all-cause yielding similar incidence rates of 4.62 (95% CI 3.14-6.87) versus 3.95 (95% CI 3.37-4.66) per 100 person-years. The adjusted risk of all-cause mortality was not significantly different in patients with versus without Type D personality with an adjusted HR of 1.31 (95% CI 0.84-2.03, p = 0.23) with similar results for cardiovascular death (HR 1.46 (95% CI 0.88-2.44, p = 0.15).

CONCLUSION:

Type D personality was not significantly associated with increased risk of all-cause mortality or cardiovascular death in patients with non-ischemic HF.
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