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One year mortality outcomes from the ACTA trial of cryptococcal meningitis treatment in Malawi.

Kanyama, Cecilia; Molloy, Síle F; Chan, Adrienne K; Lupiya, Duncan; Chawinga, Chimwemwe; Adams, Jack; Bright, Philip; Lalloo, David G; Heyderman, Robert S; Lortholary, Olivier; Jaffar, Shabbar; Loyse, Angela; van Oosterhout, Joep J; Hosseinipour, Mina C; Harrison, Thomas S.
Clin Infect Dis; 2019 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-31155650
In Malawi, 236 participants from the ACTA cryptococcal meningitis treatment trial were followed-up for 12 months. The trial outcomes reported at 10 weeks were sustained to 1 year. One-week amphotericinB plus flucytosine was associated with the lowest 1 year mortality (27.5% [95%CI: 16.3 to 44.1]).
Selo DaSilva