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Mannose Receptor and the Mystery of Nonhealing Leishmania major Infection.

Sohrabi, Yahya; Lipoldová, Marie.
Trends Parasitol; 34(5): 354-356, 2018 05.
Artigo em Inglês | MEDLINE | ID: mdl-29650366
Scientists have long puzzled over the ability of Leishmania major Seidman (LmSd) to form nonhealing cutaneous lesions in the face of a strong Th1 response. A recent study identified a population of dermal macrophages that are preferentially infected by LmSd in a mannose receptor 1-, C-type 1 (MRC1/CD206)-dependent manner.
Selo DaSilva