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Ewing's Sarcoma Family Tumors in the Jaws: Case Report, Immunohistochemical Analysis and Literature Review.

Casaroto, Ana Regina; DA Silva Sampieri, Marcelo Bonifacio; Soares, Cleverson Teixeira; DA Silva Santos, Paulo Sergio; Yaedu, Renato Yassutaka Faria; Damante, José Humberto; Lara, Vanessa Soares.
In Vivo; 31(3): 481-491, 2017 May-Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28438883
Due to the low incidence of the Ewing's Sarcoma (ES) family tumors, the available epidemiology is likely to be unreliable, and at present, there are no standard diagnostic or clinical guidelines outlining their management. This report describes a case of peripheral primitive neuroectodermal tumor (ES/pPNET) which initially mimicked cystic lesions, and describes a comparison between ES and ES/pPNET in the jaws by the World Health Organization classification. This review addressed 63 cases published in the English literature between 1950 and 2016. The majority of cases were ES. Both ES and ES/pPNET mimicked other benign entities such as traumatic, cystic and inflammatory lesions. The patients who died of their disease had a history of metastatic tumors, and primary tumor located in the mandible and maxilla for ES and ES/pPNET, respectively. The differentiation of the ES family tumors from other small blue-cell tumors may be difficult and requires familiarity with histological and immunohistochemical features.
Selo DaSilva