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Surface modification of uniaxial cyclic strain cell culture platform with temperature-responsive polymer for cell sheet detachment.

Lee, E L; Bendre, H H; Kalmykov, A; Wong, J Y.
J Mater Chem B; 3(40): 7899-7902, 2015 Oct 28.
Artigo em Inglês | MEDLINE | ID: mdl-26660468
Current cell sheet-based blood vessels lack biomimetic structure and require excessively long culture times that may compromise smooth muscle cell phenotype. We modified a commercially available product for uniaxial cell sheet conditioning with thermoresponsive copolymers. Thus, culture of detachable conditioned cell sheets is shortened while retaining structural integrity and contractility.
Selo DaSilva