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Peribulbar anesthesia in 750 patients treated with oral anticoagulants.

Calenda, Emile; Genevois, Olivier; Cardon, Annie; Muraine, Marc.
Int J Ophthalmol; 7(1): 110-3, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24634874


To check the safety of continuation of oral anticoagulants in ophthalmic procedures requiring a peribulbar anesthesia.


A prospective case control study included 750 patients with oral anticoagulants in group A and 750 patients who had never been treated with oral anticoagulant in group B. Hemorrhages were graded as follows: 1) spot ecchymosis of eyelid and or subconjunctival hemorrhage; 2) eyelid ecchymosis involving half of the lid surface area; 3) eyelid ecchymosis all around the eye, no increase in intraocular pressure; 4) retrobulbar hemorrhage with increased intraocular pressure.


In group A, grade 1 was observed in 13 patients (1.74%) and grade 2 in 2 patients (0.26%). In group B, grade 1 was observed in 12 patients (1.6%) and grade 2 was absent. No 3 or 4 hemorrhage grade was encountered in both groups. There was not significant difference in grade 1 hemorrhage between both groups (P=0.21).


Oral anticoagulants were not associated with a significant increase in potentially sight-threatening local anesthetic complications.
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