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Elevated serotonin and 5-HIAA in the brainstem and lower serotonin turnover in the prefrontal cortex of suicides.

Bach, Helene; Huang, Yung-Yu; Underwood, Mark D; Dwork, Andrew J; Mann, J John; Arango, Victoria.
Synapse; 68(3): 127-30, 2014 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-23813499
Using high pressure liquid chromatography, we find more brainstem 5-HT and 5-HIAA in suicides compared with nonpsychiatric, sudden death controls throughout the rostrocaudal extent of the brainstem DRN and MRN. This suggests that 5-HT synthesis in suicides is greater within all DRN subnuclei and the MRN compared with controls.
Selo DaSilva