Hepatocyte TNF Receptor-Associated Factor 6 Aggravates Hepatic Inflammation and Fibrosis by Promoting Lysine 6-Linked Polyubiquitination of Apoptosis Signal-Regulating Kinase 1.
Wang, Yutao; Wen, Huan; Fu, Jiajun; Cai, Lin; Li, Peng-Long; Zhao, Chang-Ling; Dong, Zhu-Feng; Ma, Jun-Peng; Wang, Xi; Tian, Han; Zhang, Yan; Liu, Ye; Cai, Jingjing; She, Zhi-Gang; Huang, Zan; Li, Wenhua; Li, Hongliang.
; 2019 Jun 20.
Artigo em Inglês | MEDLINE | ID: mdl-31222801
Mechanism of ubiquitin transfer promoted by TRAF6.
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Hepatic leukocyte immunoglobulin-like receptor B4 (LILRB4) attenuates nonalcoholic fatty liver disease via SHP1-TRAF6 pathway.
Bovine miR-146a regulates inflammatory cytokines of bovine mammary epithelial cells via targeting the TRAF6 gene.
TRAF6 regulates proliferation of stromal cells in the transition and peripheral zones of benign prostatic hyperplasia via Akt/mTOR signaling.
MicroRNA-146a-5p Negatively Regulates Pro-Inflammatory Cytokine Secretion and Cell Activation in Lipopolysaccharide Stimulated Human Hepatic Stellate Cells through Inhibition of Toll-Like Receptor 4 Signaling Pathways.
Ubiquitin-specific Protease 20 Regulates the Reciprocal Functions of ß-Arrestin2 in Toll-like Receptor 4-promoted Nuclear Factor κB (NFκB) Activation.
Tumor necrosis factor receptor-associated factor 6 (TRAF6) and TGFß-activated kinase 1 (TAK1) play essential roles in the C-type lectin receptor signaling in response to Candida albicans infection.
Alcoholic and non-alcoholic steatohepatitis.
Tumor necrosis factor receptor-associated factor (TRAF) 6 inhibition mitigates the pro-inflammatory roles and proliferation of rheumatoid arthritis fibroblast-like synoviocytes.