Aurora Kinase A Inhibition Provides Clinical Benefit, Normalizes Megakaryocytes, and Reduces Bone Marrow Fibrosis in Patients with Myelofibrosis: A Phase I Trial.
Gangat, Naseema; Marinaccio, Christian; Swords, Ronan; Watts, Justin M; Gurbuxani, Sandeep; Rademaker, Alfred; Fought, Angela J; Frankfurt, Olga; Altman, Jessica K; Wen, Qiang Jeremy; Farnoud, Noushin; Famulare, Christopher A; Patel, Akshar; Tapia, Roberto; Vallapureddy, Rangit R; Barath, Stephanie; Graf, Amy; Handlogten, Amy; Zblewski, Darci; Patnaik, Mrinal M; Al-Kali, Aref; Dinh, Yvonne Trang; Englund Prahl, Kristen; Patel, Shradha; Nobrega, Juan Carlos; Tejera, Dalissa; Thomassen, Amber; Gao, Juehua; Ji, Peng; Rampal, Raajit K; Giles, Francis J; Tefferi, Ayalew; Stein, Brady; Crispino, John D.
Clin Cancer Res
; 25(16): 4898-4906, 2019 Aug 15.
Artigo em Inglês | MEDLINE | ID: mdl-31061068
Aurora Kinase A Inhibition: A Mega-Hit for Myelofibrosis Therapy?
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