The Critical Role of RNA m<sup>6</sup>A Methylation in Cancer.
Lan, Qing; Liu, Pei Y; Haase, Jacob; Bell, Jessica L; Hüttelmaier, Stefan; Liu, Tao.
; 79(7): 1285-1292, 2019 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-30894375
Settling the m<sup>6</sup>A debate: methylation of mature mRNA is not dynamic but accelerates turnover.
m<sup>6</sup>A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover.
RNA N <sup>6</sup>-Methyladenosine Modification in Normal and Malignant Hematopoiesis.
Temporal Control of Mammalian Cortical Neurogenesis by m<sup>6</sup>A Methylation.
The m<sup>6</sup>A Writer: Rise of a Machine for Growing Tasks.
The U6 snRNA m<sup>6</sup>A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention.
m<sup>6</sup>A enhances the phase separation potential of mRNA.
m<sup>6</sup>A modification controls the innate immune response to infection by targeting type I interferons.
m<sup>6</sup>A Facilitates eIF4F-Independent mRNA Translation.
The m<sup>6</sup>A methyltransferase Ime4 epitranscriptionally regulates triacylglycerol metabolism and vacuolar morphology in haploid yeast cells.