Homozygous missense mutation L673P in adenylate kinase 7 (AK7) leads to primary male infertility and multiple morphological anomalies of the flagella but not to primary ciliary dyskinesia.
Lorès, Patrick; Coutton, Charles; Khouri, Elma El; Stouvenel, Laurence; Givelet, Maëlle; Thomas, Lucie; Rode, Baptiste; Schmitt, Alain; Louis, Bruno; Sakheli, Zeinab; Chaudhry, Marhaba; Fernandez-Gonzales, Angeles; Mitsialis, Alex; Dacheux, Denis; Wolf, Jean-Philippe; Papon, Jean-François; Gacon, Gérard; Escudier, Estelle; Arnoult, Christophe; Bonhivers, Mélanie; Savinov, Sergey N; Amselem, Serge; Ray, Pierre F; Dulioust, Emmanuel; Touré, Aminata.
Hum Mol Genet
; 2018 Dec 05.
Artigo em Inglês | MEDLINE | ID: mdl-30517620
A NIMA-Related Kinase Suppresses the Flagellar Instability Associated with the Loss of Multiple Axonemal Structures.
ICK is essential for cell type-specific ciliogenesis and the regulation of ciliary transport.
Patients with multiple morphological abnormalities of the sperm flagella due to DNAH1 mutations have a good prognosis following intracytoplasmic sperm injection.
Mutations in DNAJB13, Encoding an HSP40 Family Member, Cause Primary Ciliary Dyskinesia and Male Infertility.
Mutations in DNAH1, which encodes an inner arm heavy chain dynein, lead to male infertility from multiple morphological abnormalities of the sperm flagella.
Intraflagellar transport is required for the maintenance of the trypanosome flagellum composition but not its length.
Flagella-generated forces reveal gear-type motor in single cells of the green alga, Chlamydomonas reinhardtii.
Effect of Cell Aspect Ratio on Swarming Bacteria.
SwrD (YlzI) Promotes Swarming in Bacillus subtilis by Increasing Power to Flagellar Motors.
The geometric clutch at 20: stripping gears or gaining traction?