N<sup>6</sup>-methyladenine DNA Modification in Glioblastoma.
Xie, Qi; Wu, Tao P; Gimple, Ryan C; Li, Zheng; Prager, Briana C; Wu, Qiulian; Yu, Yang; Wang, Pengcheng; Wang, Yinsheng; Gorkin, David U; Zhang, Cheng; Dowiak, Alexis V; Lin, Kaixuan; Zeng, Chun; Sui, Yinghui; Kim, Leo J Y; Miller, Tyler E; Jiang, Li; Lee, Christine H; Huang, Zhi; Fang, Xiaoguang; Zhai, Kui; Mack, Stephen C; Sander, Maike; Bao, Shideng; Kerstetter-Fogle, Amber E; Sloan, Andrew E; Xiao, Andrew Z; Rich, Jeremy N.
; 175(5): 1228-1243.e20, 2018 11 15.
Artigo em Inglês | MEDLINE | ID: mdl-30392959
N<sup>6</sup>-Methyladenine DNA Modification in the Human Genome.
ALKBH1-Mediated tRNA Demethylation Regulates Translation.
Characterization of human AlkB homolog 1 produced in mammalian cells and demonstration of mitochondrial dysfunction in ALKBH1-deficient cells.
Biochemical Characterization of AP Lyase and m<sup>6</sup>A Demethylase Activities of Human AlkB Homologue 1 (ALKBH1).
ALKBH1 is an RNA dioxygenase responsible for cytoplasmic and mitochondrial tRNA modifications.
DNA methylation on N(6)-adenine in mammalian embryonic stem cells.
Single-nucleotide-resolution sequencing of human N6-methyldeoxyadenosine reveals strand-asymmetric clusters associated with SSBP1 on the mitochondrial genome.
Expression of Demethylase Genes, FTO and ALKBH1, Is Associated with Prognosis of Gastric Cancer.
A covalent protein-DNA 5'-product adduct is generated following AP lyase activity of human ALKBH1 (AlkB homologue 1).
AlkB Homologue 1 Demethylates <i>N</i><sup>3</sup>-Methylcytidine in mRNA of Mammals.