SNX8 modulates innate immune response to DNA virus by mediating trafficking and activation of MITA.
Wei, Jin; Lian, Huan; Guo, Wei; Chen, Yun-Da; Zhang, Xia-Nan; Zang, Ru; Zhong, Li; Yang, Qing; Hu, Ming-Ming; Luo, Wei-Wei; Shu, Hong-Bing; Li, Shu.
; 14(10): e1007336, 2018 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-30321235
Herpes Simplex Virus 1 Abrogates the cGAS/STING-Mediated Cytosolic DNA-Sensing Pathway via Its Virion Host Shutoff Protein, UL41.
A mechanism of viral immune evasion revealed by cryo-EM analysis of the TAP transporter.
USP49 negatively regulates cellular antiviral responses via deconjugating K63-linked ubiquitination of MITA.
The ATP-Dependent RNA Helicase DDX3X Modulates Herpes Simplex Virus 1 Gene Expression.
Cellular Cholesterol Facilitates the Postentry Replication Cycle of Herpes Simplex Virus 1.
Roles of Us8A and Its Phosphorylation Mediated by Us3 in Herpes Simplex Virus 1 Pathogenesis.
Structure of the herpes simplex virus 1 genome: manipulation of nicks and gaps can abrogate infectivity and alter the cellular DNA damage response.
iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING.
The Ca<sup>2+</sup> sensor STIM1 regulates the type I interferon response by retaining the signaling adaptor STING at the endoplasmic reticulum.
Neuroblastomas vary widely in their sensitivities to herpes simplex virotherapy unrelated to virus receptors and susceptibility.