Induction of programmed cell death in Trypanosoma cruzi by Lippia alba essential oils and their major and synergistic terpenes (citral, limonene and caryophyllene oxide).
Moreno, Érika Marcela; Leal, Sandra Milena; Stashenko, Elena E; García, Liliana Torcoroma.
BMC Complement Altern Med
; 18(1): 225, 2018 Jul 27.
Artigo em Inglês | MEDLINE | ID: mdl-30053848
The dinoponeratoxin peptides from the giant ant Dinoponera quadriceps display in vitro antitrypanosomal activity.
Selenium-containing analogues of WC-9 are extremely potent inhibitors of Trypanosoma cruzi proliferation.
An abietane diterpene from Salvia cuspidata and some new derivatives are active against Trypanosoma cruzi.
Synthesis and biological evaluation of quinoxaline di-N-oxide derivatives with in vitro trypanocidal activity.
An Aromatic Diamidine That Targets Kinetoplast DNA, Impairs the Cell Cycle in Trypanosoma cruzi, and Diminishes Trypomastigote Release from Infected Mammalian Host Cells.
Linalool, a Piper aduncum essential oil component, has selective activity against Trypanosoma cruzi trypomastigote forms at 4°C.
Simple dialkyl pyrazole-3,5-dicarboxylates show in vitro and in vivo activity against disease-causing trypanosomatids.
Simplifying nature: Towards the design of broad spectrum kinetoplastid inhibitors, inspired by acetogenins.
New oxirane derivatives of 1,4-naphthoquinones and their evaluation against T. cruzi epimastigote forms.
Structure-Based Virtual Screening and In Vitro Evaluation of New <i>Trypanosoma cruzi</i> Cruzain Inhibitors.