Cas4 Facilitates PAM-Compatible Spacer Selection during CRISPR Adaptation.
Kieper, Sebastian N; Almendros, Cristóbal; Behler, Juliane; McKenzie, Rebecca E; Nobrega, Franklin L; Haagsma, Anna C; Vink, Jochem N A; Hess, Wolfgang R; Brouns, Stan J J.
; 22(13): 3377-3384, 2018 03 27.
Artigo em Inglês | MEDLINE | ID: mdl-29590607
Comprehensive search for accessory proteins encoded with archaeal and bacterial type III CRISPR-cas gene cassettes reveals 39 new cas gene families.
Biochemical analysis of the Cas6-1 RNA endonuclease associated with the subtype I-D CRISPR-Cas system in Synechocystis sp. PCC 6803.
Memory Upgrade: Insights into Primed Adaptation by CRISPR-Cas Immune Systems.
RNA Guide Complementarity Prevents Self-Targeting in Type VI CRISPR Systems.
Kinetic Basis for DNA Target Specificity of CRISPR-Cas12a.
In vivo CRISPR editing with no detectable genome-wide off-target mutations.
Molecular organization of the type II-A CRISPR adaptation module and its interaction with Cas9 via Csn2.
The application of CRISPR/Cas9 in genome editing of filamentous fungi.
Two distinct DNA binding modes guide dual roles of a CRISPR-Cas protein complex.
Classification and evolution of type II CRISPR-Cas systems.