FOXP3, ICOS and ICOSL gene polymorphisms in systemic sclerosis: FOXP3 rs2294020 is associated with disease progression in a female Italian population.
D'Amico, Fabio; Fiorito, Giovanni; Skarmoutsou, Evangelia; Granata, Mariagrazia; Rossi, Giulio A; Trovato, Chiara; Bellocchi, Chiara; Marchini, Maurizio; Beretta, Lorenzo; Mazzarino, Maria Clorinda.
; 223(1): 112-117, 2018 01.
Artigo em Inglês | MEDLINE | ID: mdl-29030005
Pattern recognition receptor signaling in human dendritic cells is enhanced by ICOS ligand and modulated by the Crohn's disease ICOSLG risk allele.
ICOS:ICOS-ligand interaction is required for type 2 innate lymphoid cell function, homeostasis, and induction of airway hyperreactivity.
Local triggering of the ICOS coreceptor by CD11c(+) myeloid cells drives organ inflammation in lupus.
ICOS-Ligand Triggering Impairs Osteoclast Differentiation and Function In Vitro and In Vivo.
Association of polymorphisms in the ICOS and ICOSL genes with the pathogenesis of autoimmune thyroid diseases.
B Cell ADAM10 Controls Murine Lupus Progression through Regulation of the ICOS:ICOS Ligand Axis.
B7h triggering inhibits the migration of tumor cell lines.
Plasmacytoid dendritic cells have a cytokine-producing capacity to enhance ICOS ligand-mediated IL-10 production during T-cell priming.
Augmented ICOS expression in patients with early diffuse cutaneous systemic sclerosis.
ADAM10-Mediated ICOS Ligand Shedding on B Cells Is Necessary for Proper T Cell ICOS Regulation and T Follicular Helper Responses.