Disease-specific biases in alternative splicing and tissue-specific dysregulation revealed by multitissue profiling of lymphocyte gene expression in type 1 diabetes.
Newman, Jeremy R B; Conesa, Ana; Mika, Matthew; New, Felicia N; Onengut-Gumuscu, Suna; Atkinson, Mark A; Rich, Stephen S; McIntyre, Lauren M; Concannon, Patrick.
; 27(11): 1807-1815, 2017 11.
Artigo em Inglês | MEDLINE | ID: mdl-29025893
Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
The biology of recent thymic emigrants.
Quantifiable predictive features define epitope-specific T cell receptor repertoires.
Detection of vasostatin-1-specific CD8(+) T cells in non-obese diabetic mice that contribute to diabetes pathogenesis.
T cell receptor bias for MHC: co-evolution or co-receptors?
HIV-1-specific interleukin-21+ CD4+ T cell responses contribute to durable viral control through the modulation of HIV-specific CD8+ T cell function.
N-glycosylation bidirectionally extends the boundaries of thymocyte positive selection by decoupling Lck from Ca²âº signaling.
Multipeptide-coupled nanoparticles induce tolerance in 'humanised' HLA-transgenic mice and inhibit diabetogenic CD8<sup>+</sup> T cell responses in type 1 diabetes.
Early Transcriptional Divergence Marks Virus-Specific Primary Human CD8<sup>+</sup> T Cells in Chronic versus Acute Infection.
Immune response to a potyvirus with exposed amino groups available for chemical conjugation.