Phosphatase wild-type p53-induced phosphatase 1 controls the development of T<sub>H</sub>9 cells and allergic airway inflammation.
Wang, Peng; Su, Huiting; Zhang, Lianjun; Chen, Hui; Hu, Xuelian; Yang, Fan; Lv, Jun; Zhang, Lianfeng; Zhao, Yong.
J Allergy Clin Immunol
; 141(6): 2168-2181, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28732646
Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells.
Allergen-Induced IL-6 Regulates IL-9/IL-17A Balance in CD4+ T Cells in Allergic Airway Inflammation.
The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation.
The DNA-binding inhibitor Id3 regulates IL-9 production in CD4(+) T cells.
Basophil-derived interleukin-4 controls the function of natural helper cells, a member of ILC2s, in lung inflammation.
Retinoic Acid Receptor Alpha Represses a Th9 Transcriptional and Epigenomic Program to Reduce Allergic Pathology.
An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation.
The TNF-family ligand TL1A and its receptor DR3 promote T cell-mediated allergic immunopathology by enhancing differentiation and pathogenicity of IL-9-producing T cells.
T-bet inhibits innate lymphoid cell-mediated eosinophilic airway inflammation by suppressing IL-9 production.
A role for BATF3 in T<sub>H</sub>9 differentiation and T-cell-driven mucosal pathologies.