Neuroblast differentiation during development and in neuroblastoma requires KIF1Bß-mediated transport of TRKA.
Fell, Stuart M; Li, Shuijie; Wallis, Karin; Kock, Anna; Surova, Olga; Rraklli, Vilma; Höfig, Carolin S; Li, Wenyu; Mittag, Jens; Henriksson, Marie Arsenian; Kenchappa, Rajappa S; Holmberg, Johan; Kogner, Per; Schlisio, Susanne.
; 31(10): 1036-1053, 2017 05 15.
Artigo em Inglês | MEDLINE | ID: mdl-28637693
Proteomic analysis reveals GIT1 as a novel mTOR complex component critical for mediating astrocyte survival.
Nf1 limits epicardial derivative expansion by regulating epithelial to mesenchymal transition and proliferation.
NF1 is a tumor suppressor in neuroblastoma that determines retinoic acid response and disease outcome.
It takes a (dysfunctional) village to raise a tumor.
High response rate to PD-1 blockade in desmoplastic melanomas.
NF1 regulation of RAS/ERK signaling is required for appropriate granule neuron progenitor expansion and migration in cerebellar development.
Neurofibromina budowa i funkcje bialka w kontekscie patogenezy nerwiakowlókniakowatosci typu I.
Elucidating the impact of neurofibromatosis-1 germline mutations on neurofibromin function and dopamine-based learning.
Evidence for and against regional differences in neural stem and progenitor cells of the CNS.
Structural and biochemical consequences of NF1 associated nontruncating mutations in the Sec14-PH module of neurofibromin.