Human Virus-Derived Small RNAs Can Confer Antiviral Immunity in Mammals.
Qiu, Yang; Xu, Yanpeng; Zhang, Yao; Zhou, Hui; Deng, Yong-Qiang; Li, Xiao-Feng; Miao, Meng; Zhang, Qiang; Zhong, Bo; Hu, Yuanyang; Zhang, Fu-Chun; Wu, Ligang; Qin, Cheng-Feng; Zhou, Xi.
; 46(6): 992-1004.e5, 2017 06 20.
Artigo em Inglês | MEDLINE | ID: mdl-28636969
Neutralizing antibodies can initiate genome release from human enterovirus 71.
Crystal structures of enterovirus 71 (EV71) recombinant virus particles provide insights into vaccine design.
Structural Basis for Recognition of Human Enterovirus 71 by a Bivalent Broadly Neutralizing Monoclonal Antibody.
Enterovirus71 virus-like particles produced from insect cells and purified by multistep chromatography elicit strong humoral immune responses in mice.
Cerebrospinal fluid Th1/Th2 cytokine profiles in children with enterovirus 71-associated meningoencephalitis.
Enterovirus 71 3C inhibits cytokine expression through cleavage of the TAK1/TAB1/TAB2/TAB3 complex.
Human microRNA hsa-miR-296-5p suppresses enterovirus 71 replication by targeting the viral genome.
Monoclonal antibody against EV71 3D<sup>pol</sup> inhibits the polymerase activity of RdRp and virus replication.
[Expression and activity determination of recombinant capsid protein VP2 gene of enterovirus type 71].
Rational design of thermostable vaccines by engineered peptide-induced virus self-biomineralization under physiological conditions.