ΔNp63α is a common inhibitory target in oncogenic PI3K/Ras/Her2-induced cell motility and tumor metastasis.
Hu, Linshan; Liang, Shan; Chen, Hu; Lv, Tao; Wu, Junfeng; Chen, Deshi; Wu, Min; Sun, Shengnan; Zhang, Haibo; You, Han; Ji, Hongbin; Zhang, Yujun; Bergholz, Johann; Xiao, Zhi-Xiong Jim.
Proc Natl Acad Sci U S A
; 114(20): E3964-E3973, 2017 05 16.
Artigo em Inglês | MEDLINE | ID: mdl-28468801
FOXO3 directly regulates an autophagy network to functionally regulate proteostasis in adult neural stem cells.
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Endothelial stromelysin1 regulation by the forkhead box-O transcription factors is crucial in the exudative phase of acute lung injury.
FOXO3, estrogen receptor alpha, and androgen receptor impact tumor growth rate and infiltration of dendritic cell subsets differentially between male and female mice.
The FOXO3/PGC-1ß signaling axis is essential for cancer stem cell properties of pancreatic ductal adenocarcinoma.