CpG Island Hypermethylation Mediated by DNMT3A Is a Consequence of AML Progression.
Spencer, David H; Russler-Germain, David A; Ketkar, Shamika; Helton, Nichole M; Lamprecht, Tamara L; Fulton, Robert S; Fronick, Catrina C; O'Laughlin, Michelle; Heath, Sharon E; Shinawi, Marwan; Westervelt, Peter; Payton, Jacqueline E; Wartman, Lukas D; Welch, John S; Wilson, Richard K; Walter, Matthew J; Link, Daniel C; DiPersio, John F; Ley, Timothy J.
; 168(5): 801-816.e13, 2017 02 23.
Artigo em Inglês | MEDLINE | ID: mdl-28215704
Genomic Classification and Prognosis in Acute Myeloid Leukemia.
Therapy-related acute myeloid leukemia developing 14â¯years after allogeneic hematopoietic stem cell transplantation, from a persistent R882H-DNMT3A mutated clone of patient origin.
Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia.
Data-Driven Phenotypic Dissection of AML Reveals Progenitor-like Cells that Correlate with Prognosis.
Lifting the Differentiation Embargo.
[Effects of DNMT3A gene mutations on prognosis of patients with acute myeloid leukemia: a meta-analysis].
Conditional knockin of Dnmt3a R878H initiates acute myeloid leukemia with mTOR pathway involvement.
Prognostic significance of DNMT3A mutations in patients with acute myeloid leukemia.
Acute myeloid leukemia-associated DNMT3A p.Arg882His mutation in a patient with Tatton-Brown-Rahman overgrowth syndrome as a constitutional mutation.
A DNMT3A mutation common in AML exhibits dominant-negative effects in murine ES cells.