Human MicroRNA Responses Predict Cytomegalovirus Replication Following Solid Organ Transplantation.
Han, Sang Hoon; Kumar, Deepali; Ferreira, Victor H; Egli, Adrian; Hirsch, Hans H; Weisser, Maja; Garzoni, Christian; van Delden, Christian; Bochud, Pierre-Yves; Manuel, Oriol; Meylan, Pascal; Boggian, Katia; Husain, Shahid; Mueller, Nicolas J; Humar, Atul.
J Infect Dis
; 215(4): 537-546, 2017 02 15.
Artigo em Inglês | MEDLINE | ID: mdl-28003351
Human cytomegalovirus miR-UL112-1 promotes the down-regulation of viral immediate early-gene expression during latency to prevent T-cell recognition of latently infected cells.
Host microRNA regulation of human cytomegalovirus immediate early protein translation promotes viral latency.
An endogenous accelerator for viral gene expression confers a fitness advantage.
Analysis of human cytomegalovirus-encoded microRNA activity during infection.
Feedback-mediated signal conversion promotes viral fitness.
Human Cytomegalovirus miR-UL148D Facilitates Latent Viral Infection by Targeting Host Cell Immediate Early Response Gene 5.
miRNA-mediated targeting of human cytomegalovirus reveals biological host and viral targets of IE2.
The 5' Untranslated Region of the Major Immediate Early mRNA Is Necessary for Efficient Human Cytomegalovirus Replication.
Transcriptional dynamics reveal critical roles for non-coding RNAs in the immediate-early response.
MicroRNA High Throughput Loss-of-Function Screening Reveals an Oncogenic Role for miR-21-5p in Hodgkin Lymphoma.