novoBreak: local assembly for breakpoint detection in cancer genomes.
Chong, Zechen; Ruan, Jue; Gao, Min; Zhou, Wanding; Chen, Tenghui; Fan, Xian; Ding, Li; Lee, Anna Y; Boutros, Paul; Chen, Junjie; Chen, Ken.
; 14(1): 65-67, 2017 01.
Artigo em Inglês | MEDLINE | ID: mdl-27892959
Cancer chromosome breakpoints cluster in gene-rich genomic regions.
Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability.
Reconstructing cancer karyotypes from short read data: the half empty and half full glass.
Breakpoint profiling of 64 cancer genomes reveals numerous complex rearrangements spawned by homology-independent mechanisms.
Open adjacencies and k-breaks: detecting simultaneous rearrangements in cancer genomes.
A method for finding consensus breakpoints in the cancer genome from copy number data.
Aberrant <i>PRDM9</i> expression impacts the pan-cancer genomic landscape.
A programmable method for massively parallel targeted sequencing.
Megabase Length Hypermutation Accompanies Human Structural Variation at 17p11.2.
Translocation and deletion breakpoints in cancer genomes are associated with potential non-B DNA-forming sequences.