IL-7 and immobilized Kit-ligand stimulate serum- and stromal cell-free cultures of precursor B-cell lines and clones.
Kawano, Yohei; Petkau, Georg; Wolf, Ingrid; Tornack, Julia; Melchers, Fritz.
Eur J Immunol
; 47(1): 206-212, 2017 01.
Artigo em Inglês | MEDLINE | ID: mdl-27739072
Stage-specific control of early B cell development by the transcription factor Ikaros.
Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development.
Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemia.
Distorted antibody repertoire developed in the absence of pre-B cell receptor formation.
Pre/pro-B cells generate macrophage populations during homeostasis and inflammation.
Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia.
The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential.
4C-ing the Igh Landscape.
Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires.
Distinct Genetic Networks Orchestrate the Emergence of Specific Waves of Fetal and Adult B-1 and B-2 Development.