Repression of CMIP transcription by WT1 is relevant to podocyte health.
Moktefi, Anissa; Zhang, Shao-Yu; Vachin, Pauline; Ory, Virginie; Henique, Carole; Audard, Vincent; Rucker-Martin, Catherine; Gouadon, Elodie; Eccles, Michael; Schedl, Andreas; Heidet, Laurence; Ollero, Mario; Sahali, Djillali; Pawlak, Andre.
; 90(6): 1298-1311, 2016 12.
Artigo em Inglês | MEDLINE | ID: mdl-27650733
A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.
Clinical Aspects of WT1 and the Kidney.
A murine model of Denys-Drash syndrome reveals novel transcriptional targets of WT1 in podocytes.
WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing.
Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications.
Podloze genetyczne zespolów nerczycowych u dzieci.
Characteristics of testicular dysgenesis syndrome and decreased expression of SRY and SOX9 in Frasier syndrome.
A child with isolated nephrotic syndrome and WT1 mutation presenting as a 46, XY phenotypic male.
A proteomic investigation of glomerular podocytes from a Denys-Drash syndrome patient with a mutation in the Wilms tumour suppressor gene WT1.
Gonad development in Drash and Frasier syndromes depends on WT1 mutations.