Different Soluble Forms of the Interleukin-6 Family Signal Transducer gp130 Fine-tune the Blockade of Interleukin-6 Trans-signaling.
Wolf, Janina; Waetzig, Georg H; Chalaris, Athena; Reinheimer, Torsten M; Wege, Henning; Rose-John, Stefan; Garbers, Christoph.
J Biol Chem
; 291(31): 16186-96, 2016 07 29.
Artigo em Inglês | MEDLINE | ID: mdl-27226573
The plasma membrane: Penultimate regulator of ADAM sheddase function.
Transitional B cells commit to marginal zone B cell fate by Taok3-mediated surface expression of ADAM10.
Structural Basis for Regulated Proteolysis by the α-Secretase ADAM10.
TLR4-mediated galectin-1 production triggers epithelial-mesenchymal transition in colon cancer cells through ADAM10- and ADAM17-associated lactate production.
Insulin-like growth factor-1 activates different catalytic subunits p110 of PI3K in a cell-type-dependent manner to induce lipogenesis-dependent epithelial-mesenchymal transition through the regulation of ADAM10 and ADAM17.
The xenoestrogens biphenol-A and nonylphenol differentially regulate metalloprotease-mediated shedding of EGFR ligands.
Role of ADAM10 in intestinal crypt homeostasis and tumorigenesis.
Ectodomain shedding of the cell adhesion molecule Nectin-4 in ovarian cancer is mediated by ADAM10 and ADAM17.
Regulation of the trafficking and the function of the metalloprotease ADAM10 by tetraspanins.
Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling.