Therapeutic Administration of a Monoclonal Anti-Il-1ß Antibody Protects Against Experimental Melioidosis.
Weehuizen, Tassili A F; Lankelma, Jacqueline M; De Jong, Hanna K; De Boer, Onno J; Roelofs, Joris J T H; Day, Nicholas P; Gram, Hermann; De Vos, Alex F; Wiersinga, W Joost.
; 46(5): 566-574, 2016 11.
Artigo em Inglês | MEDLINE | ID: mdl-27219859
Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes.
[Expression of Nod-like receptor protein 3 inflammasome in peripheral blood mononuclear cells of children with Kawasaki disease in the acute stage].
PKA Has the Gall to Oppose NLRP3.
Mitochondrial respiratory-chain adaptations in macrophages contribute to antibacterial host defense.
The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation.
Aging-Associated TNF Production Primes Inflammasome Activation and NLRP3-Related Metabolic Disturbances.
[Role of NLRP3 inflammasome in the pathogenesis of alcoholic liver disease].
Activation of autophagy by inflammatory signals limits IL-1ß production by targeting ubiquitinated inflammasomes for destruction.
Inflammasome-dependent pyroptosis and IL-18 protect against Burkholderia pseudomallei lung infection while IL-1ß is deleterious.
IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.