Long-term CD4 lymphopenia is associated with accelerated decline of kidney allograft function.
Luque, Yosu; Jamme, Matthieu; Rabant, Marion; DeWolf, Susan; Noël, Laure-Hélène; Thervet, Eric; Chatenoud, Lucienne; Snanoudj, Renaud; Anglicheau, Dany; Legendre, Christophe; Candon, Sophie; Zuber, Julien.
Nephrol Dial Transplant
; 31(3): 487-95, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26492923
Rapid reconstitution of CMV-specific T-cells after stem-cell transplantation.
Risk factors for impaired CD4+ T-cell reconstitution following rabbit antithymocyte globulin treatment in kidney transplantation.
Decreased thymic output accounts for decreased naive T cell numbers in children with Down syndrome.
Lymphopenia associated with highly virulent H5N1 virus infection due to plasmacytoid dendritic cell-mediated apoptosis of T cells.
Blockade of myeloid-derived suppressor cells after induction of lymphopenia improves adoptive T cell therapy in a murine model of melanoma.
Maintenance of peripheral naive T cells is sustained by thymus output in mice but not humans.
TNFR2 is critical for the stabilization of the CD4+Foxp3+ regulatory T. cell phenotype in the inflammatory environment.
Th17 cells induce a distinct graft rejection response that does not require IL-17A.
Cutting edge: lymphoid tissue inducer cells maintain memory CD4 T cells within secondary lymphoid tissue.
Defective thymopoiesis and poor peripheral homeostatic replenishment of T-helper cells cause T-cell lymphopenia in cirrhosis.