Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background.
Elvers, Ingegerd; Turner-Maier, Jason; Swofford, Ross; Koltookian, Michele; Johnson, Jeremy; Stewart, Chip; Zhang, Cheng-Zhong; Schumacher, Steven E; Beroukhim, Rameen; Rosenberg, Mara; Thomas, Rachael; Mauceli, Evan; Getz, Gad; Palma, Federica Di; Modiano, Jaime F; Breen, Matthew; Lindblad-Toh, Kerstin; Alföldi, Jessica.
; 25(11): 1634-45, 2015 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-26377837
Genetic inactivation of TRAF3 in canine and human B-cell lymphoma.
Malaria-Induced B Cell Genomic Instability.
A TRAF-like motif of the inducible costimulator ICOS controls development of germinal center TFH cells via the kinase TBK1.
Approach to the diagnosis and treatment of high-grade B-cell lymphomas with MYC and BCL2 and/or BCL6 rearrangements.
Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis.
Clinical utility of recently identified diagnostic, prognostic, and predictive molecular biomarkers in mature B-cell neoplasms.
Conditional inactivation of p53 in mature B cells promotes generation of nongerminal center-derived B-cell lymphomas.
TET1 is a tumor suppressor of hematopoietic malignancy.
Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers.
Enhancer sequence variants and transcription-factor deregulation synergize to construct pathogenic regulatory circuits in B-cell lymphoma.