New role for the (pro)renin receptor in T-cell development.
Geisberger, Sabrina; Maschke, Ulrike; Gebhardt, Matthias; Kleinewietfeld, Markus; Manzel, Arndt; Linker, Ralf A; Chidgey, Ann; Dechend, Ralf; Nguyen, Genevieve; Daumke, Oliver; Muller, Dominik N; Wright, Mark D; Binger, Katrina J.
; 126(4): 504-7, 2015 Jul 23.
Artigo em Inglês | MEDLINE | ID: mdl-26063165
Dynamic tuning of lymphocytes: physiological basis, mechanisms, and function.
Development of interleukin-17-producing Î³Î´ T cells is restricted to a functional embryonic wave.
A non-canonical function of Ezh2 preserves immune homeostasis.
A two-amino-acid substitution in the transcription factor RORÎ³t disrupts its function in T<sub>H</sub>17 differentiation but not in thymocyte development.
Gene targeting RhoA reveals its essential role in coordinating mitochondrial function and thymocyte development.
Role of Ets Proteins in Development, Differentiation, and Function of T-Cell Subsets.
Enforcement of Î³Î´-lineage commitment by the pre-T-cell receptor in precursors with weak Î³Î´-TCR signals.
Differential requirement of RasGRP1 for Î³Î´ T cell development and activation.
Thymic involution perturbs negative selection leading to autoreactive T cells that induce chronic inflammation.
SnapShot: T Cell Exhaustion.