Identification of a Dual Inhibitor of SRPK1 and CK2 That Attenuates Pathological Angiogenesis of Macular Degeneration in Mice.
Morooka, Satoshi; Hoshina, Mitsuteru; Kii, Isao; Okabe, Takayoshi; Kojima, Hirotatsu; Inoue, Naoko; Okuno, Yukiko; Denawa, Masatsugu; Yoshida, Suguru; Fukuhara, Junichi; Ninomiya, Kensuke; Ikura, Teikichi; Furuya, Toshio; Nagano, Tetsuo; Noda, Kousuke; Ishida, Susumu; Hosoya, Takamitsu; Ito, Nobutoshi; Yoshimura, Nagahisa; Hagiwara, Masatoshi.
; 88(2): 316-25, 2015 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-25993998
Assessment of a pretomanid analogue library for African trypanosomiasis: Hit-to-lead studies on 6-substituted 2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazine 8-oxides.
Recent Development of Non-Peptide GnRH Antagonists.
Structure-based design of targeted covalent inhibitors.
Discovery of small molecule inhibitors for the snake venom metalloprotease BaP1 using in silico and in vitro tests.
Identification of Two Distinct Sites for Antagonist and Biased Agonist Binding to the Human Chemokine Receptor CXCR3.
Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes.
Synthesis and structure-activity relationships of novel, potent, orally active hypoxia-inducible factor-1 inhibitors.
Discovery and development of a small molecule library with lumazine synthase inhibitory activity.
Progress in the discovery of small molecule modulators of the Cys-loop superfamily receptors.
Identification of small molecule inhibitors of botulinum neurotoxin serotype E via footprint similarity.