Seizures are regulated by ubiquitin-specific peptidase 9 X-linked (USP9X), a de-ubiquitinase.
Paemka, Lily; Mahajan, Vinit B; Ehaideb, Salleh N; Skeie, Jessica M; Tan, Men Chee; Wu, Shu; Cox, Allison J; Sowers, Levi P; Gecz, Jozef; Jolly, Lachlan; Ferguson, Polly J; Darbro, Benjamin; Schneider, Amy; Scheffer, Ingrid E; Carvill, Gemma L; Mefford, Heather C; El-Shanti, Hatem; Wood, Stephen A; Manak, J Robert; Bassuk, Alexander G.
; 11(3): e1005022, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25763846
Crystal structure and activity-based labeling reveal the mechanisms for linkage-specific substrate recognition by deubiquitinase USP9X.
USP25 regulates Wnt signaling by controlling the stability of tankyrases.
Deubiquitination and Activation of AMPK by USP10.
USP14 regulates autophagy by suppressing K63 ubiquitination of Beclin 1.
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The exclusive effects of chaperonin on the behavior of proteins with 52 knot.
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Allosteric Activation of Ubiquitin-Specific Proteases by ß-Propeller Proteins UAF1 and WDR20.