Focused transcription from the human CR2/CD21 core promoter is regulated by synergistic activity of TATA and Initiator elements in mature B cells.
Taylor, Rhonda L; Cruickshank, Mark N; Karimi, Mahdad; Ng, Han Leng; Quail, Elizabeth; Kaufman, Kenneth M; Harley, John B; Abraham, Lawrence J; Tsao, Betty P; Boackle, Susan A; Ulgiati, Daniela.
Cell Mol Immunol
; 13(1): 119-31, 2016 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25640655
Stage-specific control of early B cell development by the transcription factor Ikaros.
Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development.
Pre/pro-B cells generate macrophage populations during homeostasis and inflammation.
Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia.
Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemia.
Distorted antibody repertoire developed in the absence of pre-B cell receptor formation.
3D trajectories adopted by coding and regulatory DNA elements: first-passage times for genomic interactions.
IL-7 and immobilized Kit-ligand stimulate serum- and stromal cell-free cultures of precursor B-cell lines and clones.
Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires.
The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential.