IL-25-responsive, lineage-negative KLRG1(hi) cells are multipotential 'inflammatory' type 2 innate lymphoid cells.
Huang, Yuefeng; Guo, Liying; Qiu, Jin; Chen, Xi; Hu-Li, Jane; Siebenlist, Ulrich; Williamson, Peter R; Urban, Joseph F; Paul, William E.
; 16(2): 161-9, 2015 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-25531830
Inflammatory ILC2 cells: disguising themselves as progenitors?
c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies.
Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161.
Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages.
A tissue checkpoint regulates type 2 immunity.
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Tuft-cell-derived IL-25 regulates an intestinal ILC2-epithelial response circuit.
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