Loss of DGKÎµ induces endothelial cell activation and death independently of complement activation.
Bruneau, Sarah; Néel, Mélanie; Roumenina, Lubka T; Frimat, Marie; Laurent, Lætitia; Frémeaux-Bacchi, Véronique; Fakhouri, Fadi.
; 125(6): 1038-46, 2015 Feb 05.
Artigo em Inglês | MEDLINE | ID: mdl-25498910
DGKE disruption ditches complement and drives p38 signaling.
HUS and atypical HUS.
The Lymphatic System: Integral Roles in Immunity.
Expression, Purification, and Properties of a Human Arachidonoyl-Specific Isoform of Diacylglycerol Kinase.
The Stromal Niche Guarding the Gatekeepers.
Phenotypic expansion of DGKE-associated diseases.
Diacylglycerol kinase Î³ regulates antigen-induced mast cell degranulation by mediating Ca(2+) influxes.
Tight regulation of diacylglycerol-mediated signaling is critical for proper invariant NKT cell development.
Diacylglycerol kinase Î´ phosphorylates phosphatidylcholine-specific phospholipase C-dependent, palmitic acid-containing diacylglycerol species in response to high glucose levels.
Experimental phasing for structure determination using membrane-protein crystals grown by the lipid cubic phase method.