Impaired development of neural-crest cell-derived organs and intellectual disability caused by MED13L haploinsufficiency.
Utami, Kagistia Hana; Winata, Cecilia Lanny; Hillmer, Axel M; Aksoy, Irene; Long, Hoang Truong; Liany, Herty; Chew, Elaine G Y; Mathavan, Sinnakaruppan; Tay, Stacey K H; Korzh, Vladimir; Sarda, Pierre; Davila, Sonia; Cacheux, Valere.
; 35(11): 1311-20, 2014 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-25137640
Subunit architecture and functional modular rearrangements of the transcriptional mediator complex.
A Computational Protein Phenotype Prediction Approach to Analyze the Deleterious Mutations of Human MED12 Gene.
Med14 cooperates with brg1 in the differentiation of skeletogenic neural crest.
Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex.
Conservation and Divergence of Mediator Structure and Function: Insights from Plants.
MED12 controls the response to multiple cancer drugs through regulation of TGF-ß receptor signaling.
Mediator MED23 plays opposing roles in directing smooth muscle cell and adipocyte differentiation.
Conservation of coactivator engagement mechanism enables small-molecule allosteric modulators.
Functional interplay between Mediator and TFIIB in preinitiation complex assembly in relation to promoter architecture.
Structure and Functions of the Mediator Complex.