The medicinal chemistry and drug development of novel antimalarials.
Curr Top Med Chem
; 14(14): 1635-6, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-25116579
2,3,8-Trisubstituted Quinolines with Antimalarial Activity.
Computational Study on the Effect of Exocyclic Substituents on the Ionization Potential of Primaquine: Insights into the Design of Primaquine-Based Antimalarial Drugs with Less Methemoglobin Generation.
Crystal structure of Plasmodium falciparum thioredoxin reductase, a validated drug target.
Design, Synthesis, and Biological Evaluation of Peptidomimetic N-Substituted Cbz-4-Hyp-Hpa-Amides as Novel Inhibitors of Plasmodium falciparum.
Synthesis, antimalarial properties and 2D-QSAR studies of novel triazole-quinine conjugates.
New Potential Antimalarial Agents: Design, Synthesis and Biological Evaluation of Some Novel Quinoline Derivatives as Antimalarial Agents.
Rational Design of Proteasome Inhibitors as Antimalarial Drugs.
Design, Synthesis, and Biological Evaluation of Novel 1,2,4-Trioxanes as Potential Antimalarial Agents.
In Silico Mining for Antimalarial Structure-Activity Knowledge and Discovery of Novel Antimalarial Curcuminoids.
Exploring clotrimazole-based pharmacophore: 3D-QSAR studies and synthesis of novel antiplasmodial agents.