Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression.
Liu, Pei Y; Erriquez, Daniela; Marshall, Glenn M; Tee, Andrew E; Polly, Patsie; Wong, Mathew; Liu, Bing; Bell, Jessica L; Zhang, Xu D; Milazzo, Giorgio; Cheung, Belamy B; Fox, Archa; Swarbrick, Alexander; Hüttelmaier, Stefan; Kavallaris, Maria; Perini, Giovanni; Mattick, John S; Dinger, Marcel E; Liu, Tao.
J Natl Cancer Inst
; 106(7)2014 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-24906397
NCYM promotes calpain-mediated Myc-nick production in human MYCN-amplified neuroblastoma cells.
Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma.
New strategies in neuroblastoma: Therapeutic targeting of MYCN and ALK.
NCYM, a Cis-antisense gene of MYCN, encodes a de novo evolved protein that inhibits GSK3ß resulting in the stabilization of MYCN in human neuroblastomas.
MYCN overexpression is associated with unbalanced copy number gain, altered nuclear location, and overexpression of chromosome arm 17q genes in neuroblastoma tumors and cell lines.
MYCN and MYC regulate tumor proliferation and tumorigenesis directly through BMI1 in human neuroblastomas.
Neuroblastoma in children: Update on clinicopathologic and genetic prognostic factors.
N-linked glycan profiling in neuroblastoma cell lines.
Telomerase activation by genomic rearrangements in high-risk neuroblastoma.
Loss of a FYN-regulated differentiation and growth arrest pathway in advanced stage neuroblastoma.