Mixed lineage kinases activate MEK independently of RAF to mediate resistance to RAF inhibitors.

Marusiak, Anna A; Edwards, Zoe C; Hugo, Willy; Trotter, Eleanor W; Girotti, Maria R; Stephenson, Natalie L; Kong, Xiangju; Gartside, Michael G; Fawdar, Shameem; Hudson, Andrew; Breitwieser, Wolfgang; Hayward, Nicholas K; Marais, Richard; Lo, Roger S; Brognard, John.
Nat Commun; 5: 3901, 2014 May 22.
Artigo em Inglês | MEDLINE | ID: mdl-24849047