LKB1 when associated with methylatedERα is a marker of bad prognosis in breast cancer.
Bouchekioua-Bouzaghou, Katia; Poulard, Coralie; Rambaud, Juliette; Lavergne, Emilie; Hussein, Nader; Billaud, Marc; Bachelot, Thomas; Chabaud, Sylvie; Mader, Sylvie; Dayan, Guila; Treilleux, Isabelle; Corbo, Laura; Le Romancer, Muriel.
Int J Cancer
; 135(6): 1307-18, 2014 Sep 15.
Artigo em Inglês | MEDLINE | ID: mdl-24615515
Liver kinase B1 expression (LKB1) is repressed by estrogen receptor alpha (ERα) in MCF-7 human breast cancer cells.
Deficiency of X-Linked Protein Kinase Nrk during Pregnancy Triggers Breast Tumor in Mice.
The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα.
SGK3 sustains ERα signaling and drives acquired aromatase inhibitor resistance through maintaining endoplasmic reticulum homeostasis.
Hippo pathway key to ploidy checkpoint.
The MPS1 family of protein kinases.
Regulation of mammalian Ste20 (Mst) kinases.
When pathways collide: collaboration and connivance among signalling proteins in development.
WNK1 kinase balances T cell adhesion versus migration in vivo.
High expression of LMTK3 is an independent factor indicating a poor prognosis in estrogen receptor α-positive breast cancer patients.