Differential regulation of the ten-eleven translocation (TET) family of dioxygenases by O-linked ß-N-acetylglucosamine transferase (OGT).
Zhang, Qiao; Liu, Xiaoguang; Gao, Wenqi; Li, Pishun; Hou, Jingli; Li, Jiwen; Wong, Jiemin.
J Biol Chem
; 289(9): 5986-96, 2014 Feb 28.
Artigo em Inglês | MEDLINE | ID: mdl-24394411
TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS.
Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics.
Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma.
Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy.
TET1 is a tumor suppressor of hematopoietic malignancy.
Endonuclease G preferentially cleaves 5-hydroxymethylcytosine-modified DNA creating a substrate for recombination.
Differential expression of ten-eleven translocation genes in endometrial cancers.
Molecular cloning of chicken TET family genes and role of chicken TET1 in erythropoiesis.
The Biochemistry of O-GlcNAc Transferase: Which Functions Make It Essential in Mammalian Cells?
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity.