Comprehensive analysis of transcriptome variation uncovers known and novel driver events in T-cell acute lymphoblastic leukemia.
Atak, Zeynep Kalender; Gianfelici, Valentina; Hulselmans, Gert; De Keersmaecker, Kim; Devasia, Arun George; Geerdens, Ellen; Mentens, Nicole; Chiaretti, Sabina; Durinck, Kaat; Uyttebroeck, Anne; Vandenberghe, Peter; Wlodarska, Iwona; Cloos, Jacqueline; Foà, Robin; Speleman, Frank; Cools, Jan; Aerts, Stein.
; 9(12): e1003997, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-24367274
Genome-wide mapping and characterization of Notch-regulated long noncoding RNAs in acute leukemia.
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Pediatric T-cell lymphoblastic leukemia evolves into relapse by clonal selection, acquisition of mutations and promoter hypomethylation.
Whole exome sequencing hints at a unique mutational profile of paediatric T-cell lymphoblastic lymphoma.
Activation of the <i>LMO2</i> oncogene through a somatically acquired neomorphic promoter in T-cell acute lymphoblastic leukemia.
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