Circulating precursor CCR7(lo)PD-1(hi) CXCR5âº CD4âº T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.
He, Jing; Tsai, Louis M; Leong, Yew Ann; Hu, Xin; Ma, Cindy S; Chevalier, Nina; Sun, Xiaolin; Vandenberg, Kirsten; Rockman, Steve; Ding, Yan; Zhu, Lei; Wei, Wei; Wang, Changqi; Karnowski, Alexander; Belz, Gabrielle T; Ghali, Joanna R; Cook, Matthew C; Riminton, D Sean; Veillette, André; Schwartzberg, Pamela L; Mackay, Fabienne; Brink, Robert; Tangye, Stuart G; Vinuesa, Carola G; Mackay, Charles R; Li, Zhanguo; Yu, Di.
; 39(4): 770-81, 2013 Oct 17.
Artigo em Inglês | MEDLINE | ID: mdl-24138884
Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance.
Follicular Helper T Cells.
Follicular helper CD4 T cells (TFH).
Human circulating PD-1+CXCR3-CXCR5+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses.
PD-1 Controls Follicular T Helper Cell Positioning and Function.
A novel mouse model for tracking the fate of CXCR5-expressing T cells.
Plasticity of Th17 cells in Peyer's patches is responsible for the induction of T cell-dependent IgA responses.
Location, Location, Location.
T Follicular Helper Cell Biology: A Decade of Discovery and Diseases.
Transcriptional and epigenetic control of T helper cell specification: molecular mechanisms underlying commitment and plasticity.