C-type lectin receptors Dectin-3 and Dectin-2 form a heterodimeric pattern-recognition receptor for host defense against fungal infection.
Zhu, Le-Le; Zhao, Xue-Qiang; Jiang, Changying; You, Yun; Chen, Xiao-Ping; Jiang, Yuan-Ying; Jia, Xin-Ming; Lin, Xin.
; 39(2): 324-34, 2013 Aug 22.
Artigo em Inglês | MEDLINE | ID: mdl-23911656
Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens.
Signaling by myeloid C-type lectin receptors in immunity and homeostasis.
Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate.
Mouse mincle: characterization as a model for human mincle and evolutionary implications.
Tyrosine phosphatase SHP-2 mediates C-type lectin receptor-induced activation of the kinase Syk and anti-fungal TH17 responses.
Macrophage C-type lectin is essential for phagosome maturation and acidification during Escherichia coli-induced peritonitis.
Identification of a dendritic cell receptor that couples sensing of necrosis to immunity.
C-type lectin MCL is an FcRÎ³-coupled receptor that mediates the adjuvanticity of mycobacterial cord factor.
Mincle Signaling Promotes Con A Hepatitis.
Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity.