Temozolomide down-regulates P-glycoprotein in human blood-brain barrier cells by disrupting Wnt3 signaling.
Riganti, Chiara; Salaroglio, Iris C; Pinzòn-Daza, Martha L; Caldera, Valentina; Campia, Ivana; Kopecka, Joanna; Mellai, Marta; Annovazzi, Laura; Couraud, Pierre-Olivier; Bosia, Amalia; Ghigo, Dario; Schiffer, Davide.
Cell Mol Life Sci
; 71(3): 499-516, 2014 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-23771630
The regrowth kinetic of the surviving population is independent of acute and chronic responses to temozolomide in glioblastoma cell lines.
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Temozolomide may induce cell cycle arrest by interacting with URG4/URGCP in SH-SY5Y neuroblastoma cells.