The anti-genomic (negative) strand of Hepatitis C Virus is not targetable by shRNA.
Lisowski, Leszek; Elazar, Menashe; Chu, Kirk; Glenn, Jeffrey S; Kay, Mark A.
Nucleic Acids Res
; 41(6): 3688-98, 2013 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-23396439
The Coding Region of the HCV Genome Contains a Network of Regulatory RNA Structures.
Detection and characterization of a novel hepacivirus in long-tailed ground squirrels (Spermophilus undulatus) in China.
Weak base pairing in both seed and 3' regions reduces RNAi off-targets and enhances si/shRNA designs.
Pioneering a Global Cure for Chronic Hepatitis C Virus Infection.
Gene therapies for hepatitis C virus.
Conserved RNA secondary structures and long-range interactions in hepatitis C viruses.
Internal Disequilibria and Phenotypic Diversification during Replication of Hepatitis C Virus in a Noncoevolving Cellular Environment.
[Recognition mechanism of hepatitis C viral infection].
A twist in the tail: SHAPE mapping of long-range interactions and structural rearrangements of RNA elements involved in HCV replication.
Are trans-complementation systems suitable for hepatitis C virus life cycle studies?