miR-21 mediates hematopoietic suppression in MDS by activating TGF-ß signaling.
Bhagat, Tushar D; Zhou, Li; Sokol, Lubomir; Kessel, Rachel; Caceres, Gisela; Gundabolu, Krishna; Tamari, Roni; Gordon, Shanisha; Mantzaris, Ioannis; Jodlowski, Tomasz; Yu, Yiting; Jing, Xiaohong; Polineni, Rahul; Bhatia, Kavi; Pellagatti, Andrea; Boultwood, Jacqueline; Kambhampati, Suman; Steidl, Ulrich; Stein, Cy; Ju, Wenjun; Liu, Gang; Kenny, Paraic; List, Alan; Bitzer, Markus; Verma, Amit.
; 121(15): 2875-81, 2013 Apr 11.
Artigo em Inglês | MEDLINE | ID: mdl-23390194
Xist RNA is a potent suppressor of hematologic cancer in mice.
Genetics factors associated with myelodysplastic syndromes.
The role of ASXL1 in hematopoiesis and myeloid malignancies.
The role of microRNA in myelodysplastic syndromes: beyond DNA methylation and histone modification.
MDS-associated somatic mutations and clonal hematopoiesis are common in idiopathic cytopenias of undetermined significance.
Loss of Asxl1 leads to myelodysplastic syndrome-like disease in mice.
Recent developments in myelodysplastic syndromes.
TP53 overexpression is an independent adverse prognostic factor in de novo myelodysplastic syndromes with fibrosis.
MDS with isolated del(5q) and internuclear bridging.
Profile of fibrosis-related gene transcripts and megakaryocytic changes in the bone marrow of myelodysplastic syndromes with fibrosis.